Although fuel consumption varies not only by type of aircraft but by factors like speed, headwinds, and cargo weight, a 747 jet uses about 1 gallon of fuel every SECOND. However, the plane can carry so many people that really it’s as if it’s getting 100 miles per gallon for every person. Of course, you can fit more than one person in a car, too, so how are you supposed to figure out if it makes more sense to drive or fly?
For a detailed explanation, check out howstuffworks and the links it suggests.